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Book Review

Bioinformatics for Geneticists: A Bioinformatics Primer for the Analysis of Genetic Data

Andrew D. Johnson, PhD

Framingham Heart Study, National Heart, Lung, and Blood Institute, Framingham, Mass

An extract of the first 250 words of the full text is provided, because this article has no abstract.

	Introduction

 
Michael R. Barnes, ed
554 pages. England, UK: John Wiley & Sons; 2007. 2nd ed. $90.00. Paperback. ISBN 978-0-470-02620-5

This book, now in its second edition for more than a year, is positioned at the intersection of disciplines including genetics, bioinformatics (the melding of computer science and biology), biomedical research, and molecular biology. Over 19 chapters, the authors cover an impressive terrain. The focus is mainly on human genetics and genomics, with research in other species also presented, particularly where it supports and advances our understanding of human genetics. Although a thoughtful discussion of the relevant literature and techniques is found in each chapter, the book is not overly technical and does not present advanced mathematical, statistical, or genetic concepts in great depth. Instead, the focus is on practical applications, available tools, software, and databases, and the presentation of supporting real world research examples. The end result is one of the best available and most accessible texts on bioinformatics and genetics in the postgenome age.

This book is recommended for at least 4 groups of individuals: (1) geneticists, who may gain knowledge of tools to increase the speed, breadth, and depth of their research and help in navigating the vast space of available browsers and databases; (2) bioinformaticians, often trained in specific subdisciplines and sometimes lacking the vocabulary to communicate with geneticists, will gain a working understanding of major issues in genetics and likely discover new bioinformatics tools they were unaware of; (3) molecular scientists, who will gain valuable insight . . . [Full Text of this Article]