Epidemiology, Lifestyle, and Prevention

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Use of Clinical Exome Sequencing in Isolated Congenital Heart Disease
Laura Zahavich, Sarah Bowdin and Seema Mital

Circulation: Genomic and Precision Medicine. 2017;10:e001581, originally published May 4, 2017
https://doi.org/10.1161/CIRCGENETICS.116.001581

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Genome-Wide Association Studies and Meta-Analyses for Congenital Heart DefectsCLINICAL PERSPECTIVE
A. J. Agopian, Elizabeth Goldmuntz, Hakon Hakonarson, Anshuman Sewda, Deanne Taylor and Laura E. Mitchell Pediatric Cardiac Genomics Consortium*

Circulation: Genomic and Precision Medicine. 2017;10:e001449, originally published May 3, 2017
https://doi.org/10.1161/CIRCGENETICS.116.001449

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Are Double Mutations Double Trouble?
Diane Fatkin and Renee Johnson

Circulation: Genomic and Precision Medicine. 2017;10:e001749, originally published April 18, 2017
https://doi.org/10.1161/CIRCGENETICS.117.001749

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Socioeconomic Status Interacts with the Genetic Effect of a Chromosome 9p21.3 Common Variant to Influence Coronary Artery Calcification and Incident Coronary Events in the Heinz Nixdorf Recall Study (Risk Factors, Evaluation of Coronary Calcium, and Lifestyle)CLINICAL PERSPECTIVE
Börge Schmidt, Stefanie Frölich, Nico Dragano, Mirjam Frank, Lewin Eisele, Sonali Pechlivanis, Andreas J. Forstner, Markus M. Nöthen, Amir A. Mahabadi, Raimund Erbel, Susanne Moebus and Karl-Heinz Jöckel

Circulation: Genomic and Precision Medicine. 2017;10:e001441, originally published April 14, 2017
https://doi.org/10.1161/CIRCGENETICS.116.001441

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Delivering Clinical Grade Sequencing and Genetic Test Interpretation for Cardiovascular Medicine
Andrew R. Harper, Victoria N. Parikh, Rachel L. Goldfeder, Colleen Caleshu and Euan A. Ashley

Circulation: Genomic and Precision Medicine. 2017;10:e001221, originally published April 14, 2017
https://doi.org/10.1161/CIRCGENETICS.116.001221

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Admixture Mapping of Subclinical Atherosclerosis and Subsequent Clinical Events Among African Americans in 2 Large Cohort StudiesCLINICAL PERSPECTIVE
Aditi Shendre, Howard Wiener, Marguerite R. Irvin, Degui Zhi, Nita A. Limdi, Edgar T. Overton, Christina L. Wassel, Jasmin Divers, Jerome I. Rotter, Wendy S. Post and Sadeep Shrestha

Circulation: Genomic and Precision Medicine. 2017;10:e001569, originally published April 13, 2017
https://doi.org/10.1161/CIRCGENETICS.116.001569

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Heritability of the Severity of the Metabolic Syndrome in Whites and Blacks in 3 Large CohortsCLINICAL PERSPECTIVE
Solomon K. Musani, Lisa J. Martin, Jessica G. Woo, Michael Olivier, Matthew J. Gurka and Mark D. DeBoer

Circulation: Genomic and Precision Medicine. 2017;10:e001621, originally published April 13, 2017
https://doi.org/10.1161/CIRCGENETICS.116.001621

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Epigenetic Patterns in Blood Associated With Lipid Traits Predict Incident Coronary Heart Disease Events and Are Enriched for Results From Genome-Wide Association StudiesCLINICAL PERSPECTIVE
Åsa K. Hedman, Michael M. Mendelson, Riccardo E. Marioni, Stefan Gustafsson, Roby Joehanes, Marguerite R. Irvin, Degui Zhi, Johanna K. Sandling, Chen Yao, Chunyu Liu, Liming Liang, Tianxiao Huan, Allan F. McRae, Serkalem Demissie, Sonia Shah, John M. Starr, L. Adrienne Cupples, Panos Deloukas, Timothy D. Spector, Johan Sundström, Ronald M. Krauss, Donna K. Arnett, Ian J. Deary, Lars Lind, Daniel Levy and Erik Ingelsson

Circulation: Genomic and Precision Medicine. 2017;10:e001487, originally published February 17, 2017
https://doi.org/10.1161/CIRCGENETICS.116.001487

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Novel Variant in the ANK2 Membrane-Binding Domain Is Associated With Ankyrin-B Syndrome and Structural Heart Disease in a First Nations Population With a High Rate of Long QT SyndromeCLINICAL PERSPECTIVE
Leigh Anne Swayne, Nathaniel P. Murphy, Sirisha Asuri, Lena Chen, Xiaoxue Xu, Sarah McIntosh, Chao Wang, Peter J. Lancione, Jason D. Roberts, Charles Kerr, Shubhayan Sanatani, Elizabeth Sherwin, Crystal F. Kline, Mingjie Zhang, Peter J. Mohler and Laura T. Arbour

Circulation: Genomic and Precision Medicine. 2017;10:e001537, originally published February 14, 2017
https://doi.org/10.1161/CIRCGENETICS.116.001537

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Functional Validation of a Common Nonsynonymous Coding Variant in ZC3HC1 Associated With Protection From Coronary Artery DiseaseCLINICAL PERSPECTIVE
Tara Linseman, Sébastien Soubeyrand, Amy Martinuk, Majid Nikpay, Paulina Lau and Ruth McPherson

Circulation: Genomic and Precision Medicine. 2017;10:e001498, originally published January 23, 2017
https://doi.org/10.1161/CIRCGENETICS.116.001498

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