Epidemiology, Lifestyle, and Prevention

  • Pharmacogenomic Determinants of the Cardiovascular Effects of DalcetrapibCLINICAL PERSPECTIVE
    Jean-Claude Tardif, Eric Rhéaume, Louis-Philippe Lemieux Perreault, Jean C. Grégoire, Yassamin Feroz Zada, Géraldine Asselin, Sylvie Provost, Amina Barhdadi, David Rhainds, Philippe L. L’Allier, Reda Ibrahim, Ruchi Upmanyu, Eric J. Niesor, Renée Benghozi, Gabriela Suchankova, Fouzia Laghrissi-Thode, Marie-Claude Guertin, Anders G. Olsson, Ian Mongrain, Gregory G. Schwartz and Marie-Pierre Dubé
    Circulation: Cardiovascular Genetics. 2015;8:372-382, originally published January 11, 2015
    https://doi.org/10.1161/CIRCGENETICS.114.000663
  • Integrated Metabolomics and GenomicsSystems Approaches to Biomarkers and Mechanisms of Cardiovascular Disease
    Svati H. Shah and Christopher B. Newgard
    Circulation: Cardiovascular Genetics. 2015;8:410-419, originally published April 21, 2015
    https://doi.org/10.1161/CIRCGENETICS.114.000223
  • Multiethnic Genome-Wide Association Study of Cerebral White Matter Hyperintensities on MRICLINICAL PERSPECTIVE
    Benjamin F.J. Verhaaren, Stéphanie Debette, Joshua C. Bis, Jennifer A. Smith, M. Kamran Ikram, Hieab H. Adams, Ashley H. Beecham, Kumar B. Rajan, Lorna M. Lopez, Sandra Barral, Mark A. van Buchem, Jeroen van der Grond, Albert V. Smith, Katrin Hegenscheid, Neelum T. Aggarwal, Mariza de Andrade, Elizabeth J. Atkinson, Marian Beekman, Alexa S. Beiser, Susan H. Blanton, Eric Boerwinkle, Adam M. Brickman, R. Nick Bryan, Ganesh Chauhan, Christopher P.L.H. Chen, Vincent Chouraki, Anton J.M. de Craen, Fabrice Crivello, Ian J. Deary, Joris Deelen, Philip L. De Jager, Carole Dufouil, Mitchell S.V. Elkind, Denis A. Evans, Paul Freudenberger, Rebecca F. Gottesman, Vilmundur Guðnason, Mohamad Habes, Susan R. Heckbert, Gerardo Heiss, Saima Hilal, Edith Hofer, Albert Hofman, Carla A. Ibrahim-Verbaas, David S. Knopman, Cora E. Lewis, Jiemin Liao, David C.M. Liewald, Michelle Luciano, Aad van der Lugt, Oliver O. Martinez, Richard Mayeux, Bernard Mazoyer, Mike Nalls, Matthias Nauck, Wiro J. Niessen, Ben A. Oostra, Bruce M. Psaty, Kenneth M. Rice, Jerome I. Rotter, Bettina von Sarnowski, Helena Schmidt, Pamela J. Schreiner, Maaike Schuur, Stephen S. Sidney, Sigurdur Sigurdsson, P. Eline Slagboom, David J.M. Stott, John C. van Swieten, Alexander Teumer, Anna Maria Töglhofer, Matthew Traylor, Stella Trompet, Stephen T. Turner, Christophe Tzourio, Hae-Won Uh, André G. Uitterlinden, Meike W. Vernooij, Jing J. Wang, Tien Y. Wong, Joanna M. Wardlaw, B. Gwen Windham, Katharina Wittfeld, Christiane Wolf, Clinton B. Wright, Qiong Yang, Wei Zhao, Alex Zijdenbos, J. Wouter Jukema, Ralph L. Sacco, Sharon L.R. Kardia, Philippe Amouyel, Thomas H. Mosley, W. T. Longstreth, Charles C. DeCarli, Cornelia M. van Duijn, Reinhold Schmidt, Lenore J. Launer, Hans J. Grabe, Sudha S. Seshadri, M. Arfan Ikram and Myriam Fornage
    Circulation: Cardiovascular Genetics. 2015;8:398-409, originally published February 7, 2015
    https://doi.org/10.1161/CIRCGENETICS.114.000858
  • Genome-Wide Association Study for Endothelial Growth FactorsCLINICAL PERSPECTIVE
    Wolfgang Lieb, Ming-Huei Chen, Martin G. Larson, Radwan Safa, Alexander Teumer, Sebastian E. Baumeister, Honghuang Lin, Holly M. Smith, Manja Koch, Roberto Lorbeer, Uwe Völker, Matthias Nauck, Henry Völzke, Henri Wallaschofski, Douglas B. Sawyer and Ramachandran S. Vasan
    Circulation: Cardiovascular Genetics. 2015;8:389-397, originally published December 31, 2014
    https://doi.org/10.1161/CIRCGENETICS.114.000597
  • Clinically Significant Novel Biomarkers for Prediction of First Ever Myocardial InfarctionCLINICAL PERSPECTIVEThe Tromsø Study
    Tom Wilsgaard, Ellisiv Bøgeberg Mathiesen, Anil Patwardhan, Michael W. Rowe, Henrik Schirmer, Maja-Lisa Løchen, Julie Sudduth-Klinger, Sarah Hamren, Kaare Harald Bønaa and Inger Njølstad
    Circulation: Cardiovascular Genetics. 2015;8:363-371, originally published January 22, 2015
    https://doi.org/10.1161/CIRCGENETICS.113.000630
  • Chasing—and Catching—the Wild GooseHypothesis-Free Post-Hoc Stratification Studies as a New Paradigm for Drug Development
    Klaus Lindpaintner
    Circulation: Cardiovascular Genetics. 2015;8:253-255, originally published April 21, 2015
    https://doi.org/10.1161/CIRCGENETICS.115.001037
  • Deciphering Unexplained Familial DyslipidemiasDo We Have the Tools?
    Heribert Schunkert and Felix Bourier
    Circulation: Cardiovascular Genetics. 2015;8:250-252, originally published April 21, 2015
    https://doi.org/10.1161/CIRCGENETICS.115.001066
  • Systems Biology With High-Throughput Sequencing Reveals Genetic Mechanisms Underlying the Metabolic Syndrome in the Lyon Hypertensive RatCLINICAL PERSPECTIVE
    Jinkai Wang, Man Chun John Ma, Amanda K. Mennie, Janette M. Pettus, Yang Xu, Lan Lin, Matthew G. Traxler, Jessica Jakoubek, Santosh S. Atanur, Timothy J. Aitman, Yi Xing and Anne E. Kwitek
    Circulation: Cardiovascular Genetics. 2015;8:316-326, originally published January 8, 2015
    https://doi.org/10.1161/CIRCGENETICS.114.000520
  • DNA Methylation of Lipid-Related Genes Affects Blood Lipid LevelsCLINICAL PERSPECTIVE
    Liliane Pfeiffer, Simone Wahl, Luke C. Pilling, Eva Reischl, Johanna K. Sandling, Sonja Kunze, Lesca M. Holdt, Anja Kretschmer, Katharina Schramm, Jerzy Adamski, Norman Klopp, Thomas Illig, Åsa K. Hedman, Michael Roden, Dena G. Hernandez, Andrew B. Singleton, Wolfgang E. Thasler, Harald Grallert, Christian Gieger, Christian Herder, Daniel Teupser, Christa Meisinger, Timothy D. Spector, Florian Kronenberg, Holger Prokisch, David Melzer, Annette Peters, Panos Deloukas, Luigi Ferrucci and Melanie Waldenberger
    Circulation: Cardiovascular Genetics. 2015;8:334-342, originally published January 12, 2015
    https://doi.org/10.1161/CIRCGENETICS.114.000804
  • Serum Lipid Levels, Body Mass Index, and Their Role in Coronary Artery CalcificationCLINICAL PERSPECTIVEA Polygenic Analysis
    Jessica van Setten, Ivana Išgum, Sonali Pechlivanis, Vinicius Tragante, Pim A. de Jong, Joanna Smolonska, Mathieu Platteel, Per Hoffmann, Matthijs Oudkerk, Harry J. de Koning, Markus M. Nöthen, Susanne Moebus, Raimund Erbel, Karl-Heinz Jöckel, Max A. Viergever, Willem P.Th.M. Mali and Paul I.W. de Bakker
    Circulation: Cardiovascular Genetics. 2015;8:327-333, originally published January 10, 2015
    https://doi.org/10.1161/CIRCGENETICS.114.000496

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