Heart Failure and Cardiac Disease

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SPARCling Study of a Drosophila Cardiomyopathy
Matthew J. Wolf

Circulation: Genomic and Precision Medicine. 2016;9:104-106, originally published April 19, 2016
https://doi.org/10.1161/CIRCGENETICS.116.001394

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SPARC–Dependent Cardiomyopathy in DrosophilaCLINICAL PERSPECTIVE
Paul S. Hartley, Khatereh Motamedchaboki, Rolf Bodmer and Karen Ocorr

Circulation: Genomic and Precision Medicine. 2016;9:119-129, originally published February 2, 2016
https://doi.org/10.1161/CIRCGENETICS.115.001254

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Exome Sequencing Identified a Splice Site Mutation in FHL1 that Causes Uruguay Syndrome, an X-Linked Disorder With Skeletal Muscle Hypertrophy and Premature Cardiac DeathCLINICAL PERSPECTIVE
Yuan Xue, Benedikt Schoser, Aliz R. Rao, Roberto Quadrelli, Alicia Vaglio, Verena Rupp, Christine Beichler, Stanley F. Nelson, Gudrun Schapacher-Tilp, Christian Windpassinger and William R. Wilcox

Circulation: Genomic and Precision Medicine. 2016;9:130-135, originally published March 1, 2016
https://doi.org/10.1161/CIRCGENETICS.115.001193

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Genetic Risk Scores Predict Recurrence of Acute Coronary SyndromeCLINICAL PERSPECTIVE
Satu Vaara, Emmi Tikkanen, Olavi Parkkonen, Marja-Liisa Lokki, Samuli Ripatti, Markus Perola, Markku S. Nieminen and Juha Sinisalo

Circulation: Genomic and Precision Medicine. 2016;9:172-178, originally published March 15, 2016
https://doi.org/10.1161/CIRCGENETICS.115.001271

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Unraveling De Novo Copy Number Variants in Congenital Heart DefectsThe Bottom of the Iceberg Is Under Attack
Patrice Bouvagnet

Circulation: Genomic and Precision Medicine. 2016;9:4-5, originally published February 16, 2016
https://doi.org/10.1161/CIRCGENETICS.116.001360

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Application of Genetic Testing in Hypertrophic Cardiomyopathy for Preclinical Disease Detection
Jodie Ingles, Charlotte Burns, Alexandra Barratt and Christopher Semsarian

Circulation: Genomic and Precision Medicine. 2015;8:852-859, originally published December 15, 2015
https://doi.org/10.1161/CIRCGENETICS.115.001093

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Green Tea Catechin Normalizes the Enhanced Ca²⁺ Sensitivity of Myofilaments Regulated by a Hypertrophic Cardiomyopathy–Associated Mutation in Human Cardiac Troponin I (K206I)CLINICAL PERSPECTIVE
Chad M. Warren, Chehade N. Karam, Beata M. Wolska, Tomoyoshi Kobayashi, Pieter P. de Tombe, Grace M. Arteaga, J. Martijn Bos, Michael J. Ackerman and R. John Solaro

Circulation: Genomic and Precision Medicine. 2015;8:765-773, originally published November 9, 2015
https://doi.org/10.1161/CIRCGENETICS.115.001234

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Eya4 Induces Hypertrophy via Regulation of p27^kip1CLINICAL PERSPECTIVE
Tatjana Williams, Moritz Hundertmark, Peter Nordbeck, Sabine Voll, Paula Anahi Arias-Loza, Daniel Oppelt, Melanie Mühlfelder, Susanna Schraut, Ines Elsner, Martin Czolbe, Lea Seidlmayer, Britta Heinze, Stefanie Hahner, Katrin Heinze, Jost Schönberger, Peter Jakob and Oliver Ritter

Circulation: Genomic and Precision Medicine. 2015;8:752-764, originally published October 23, 2015
https://doi.org/10.1161/CIRCGENETICS.115.001134

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Calcium Signaling Pathway Genes RUNX2 and CACNA1C Are Associated With Calcific Aortic Valve DiseaseCLINICAL PERSPECTIVE
Sandra Guauque-Olarte, David Messika-Zeitoun, Arnaud Droit, Maxime Lamontagne, Joël Tremblay-Marchand, Emilie Lavoie-Charland, Nathalie Gaudreault, Benoit J. Arsenault, Marie-Pierre Dubé, Jean-Claude Tardif, Simon C. Body, Jonathan G. Seidman, Catherine Boileau, Patrick Mathieu, Philippe Pibarot and Yohan Bossé

Circulation: Genomic and Precision Medicine. 2015;8:812-822, originally published November 9, 2015
https://doi.org/10.1161/CIRCGENETICS.115.001145

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Cardiac Disease Status Dictates Functional mRNA Targeting Profiles of Individual MicroRNAsCLINICAL PERSPECTIVE
Scot J. Matkovich, Gerald W. Dorn, Tiffani C. Grossenheider and Peter A. Hecker

Circulation: Genomic and Precision Medicine. 2015;8:774-784, originally published November 9, 2015
https://doi.org/10.1161/CIRCGENETICS.115.001237

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