Mechanisms

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Functional Validation of a Common Nonsynonymous Coding Variant in ZC3HC1 Associated With Protection From Coronary Artery DiseaseCLINICAL PERSPECTIVE
Tara Linseman, Sébastien Soubeyrand, Amy Martinuk, Majid Nikpay, Paulina Lau and Ruth McPherson

Circulation: Cardiovascular Genetics. 2017;10:e001498, originally published January 23, 2017
https://doi.org/10.1161/CIRCGENETICS.116.001498

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Letter by Amin et al Regarding Article, “Genetic Modifiers for the Long-QT Syndrome: How Important Is the Role of Variants in the 3′ Untranslated Region of KCNQ1?”
Ahmad S. Amin, Yigal M. Pinto, Michael J. Ackerman and Arthur A.M. Wilde

Circulation: Cardiovascular Genetics. 2016;9:580, originally published December 20, 2016
https://doi.org/10.1161/CIRCGENETICS.116.001629

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Sucrose Nonfermenting-Related Kinase Enzyme–Mediated Rho-Associated Kinase Signaling is Responsible for Cardiac FunctionCLINICAL PERSPECTIVE
Stephanie M. Cossette, Vijesh J. Bhute, Xiaoping Bao, Leanne M. Harmann, Mark A. Horswill, Indranil Sinha, Adam Gastonguay, Shabnam Pooya, Michelle Bordas, Suresh N. Kumar, Shama P. Mirza, Sean P. Palecek, Jennifer L. Strande and Ramani Ramchandran

Circulation: Cardiovascular Genetics. 2016;9:474-486, originally published October 25, 2016
https://doi.org/10.1161/CIRCGENETICS.116.001515

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Genetic Modifiers for the Long-QT SyndromeClinical PerspectiveHow Important Is the Role of Variants in the 3′ Untranslated Region of KCNQ1?
Lia Crotti, Annukka M. Lahtinen, Carla Spazzolini, Elisa Mastantuono, Maria Cristina Monti, Caterina Morassutto, Gianfranco Parati, Marshall Heradien, Althea Goosen, Peter Lichtner, Thomas Meitinger, Paul A. Brink, Kimmo Kontula, Heikki Swan and Peter J. Schwartz

Circulation: Cardiovascular Genetics. 2016;9:330-339, originally published August 16, 2016
https://doi.org/10.1161/CIRCGENETICS.116.001419

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Exome Sequencing Identified a Splice Site Mutation in FHL1 that Causes Uruguay Syndrome, an X-Linked Disorder With Skeletal Muscle Hypertrophy and Premature Cardiac DeathCLINICAL PERSPECTIVE
Yuan Xue, Benedikt Schoser, Aliz R. Rao, Roberto Quadrelli, Alicia Vaglio, Verena Rupp, Christine Beichler, Stanley F. Nelson, Gudrun Schapacher-Tilp, Christian Windpassinger and William R. Wilcox

Circulation: Cardiovascular Genetics. 2016;9:130-135, originally published March 1, 2016
https://doi.org/10.1161/CIRCGENETICS.115.001193

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Genome-Wide Association Study for Endothelial Growth FactorsCLINICAL PERSPECTIVE
Wolfgang Lieb, Ming-Huei Chen, Martin G. Larson, Radwan Safa, Alexander Teumer, Sebastian E. Baumeister, Honghuang Lin, Holly M. Smith, Manja Koch, Roberto Lorbeer, Uwe Völker, Matthias Nauck, Henry Völzke, Henri Wallaschofski, Douglas B. Sawyer and Ramachandran S. Vasan

Circulation: Cardiovascular Genetics. 2015;8:389-397, originally published December 31, 2014
https://doi.org/10.1161/CIRCGENETICS.114.000597

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Does Our Gut Microbiome Predict Cardiovascular Risk?A Review of the Evidence From Metabolomics
Julian L. Griffin, Xinzhu Wang and Elizabeth Stanley

Circulation: Cardiovascular Genetics. 2015;8:187-191, originally published February 17, 2015
https://doi.org/10.1161/CIRCGENETICS.114.000219

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LipidomicsQuest for Molecular Lipid Biomarkers in Cardiovascular Disease
Helmut Hinterwirth, Christin Stegemann and Manuel Mayr

Circulation: Cardiovascular Genetics. 2014;7:941-954, originally published December 16, 2014
https://doi.org/10.1161/CIRCGENETICS.114.000550

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Emerging Epigenetic Maps in Atherosclerosis
Jorge Plutzky

Circulation: Cardiovascular Genetics. 2014;7:573-575, originally published October 21, 2014
https://doi.org/10.1161/CIRCGENETICS.114.000829

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Tracing the Proteomic Fingerprint of the Diabetic Aorta?
Gonca Suna and Manuel Mayr

Circulation: Cardiovascular Genetics. 2014;7:100-101, originally published April 15, 2014
https://doi.org/10.1161/CIRCGENETICS.114.000592

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