Quality and Outcomes

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Variants of Uncertain SignificanceShould We Revisit How They Are Evaluated and Disclosed?
Ana Morales and Ray E. Hershberger

Circ Genom Precis Med. 2018;11:e002169, originally published May 30, 2018
https://doi.org/10.1161/CIRCGEN.118.002169

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Ability of Patients to Distinguish Among Cardiac Genomic Variant Subclassifications
Lydia D. Hellwig, Barbara B. Biesecker, Katie L. Lewis, Leslie G. Biesecker, Cynthia A. James and William M.P. Klein

Circ Genom Precis Med. 2018;11:e001975, originally published May 30, 2018
https://doi.org/10.1161/CIRCGEN.117.001975

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Interdisciplinary Models for Research and Clinical Endeavors in Genomic Medicine: A Scientific Statement From the American Heart Association
Kiran Musunuru, Pankaj Arora, John P. Cooke, Jane F. Ferguson, Ray E. Hershberger, Kathleen T. Hickey, Jin-Moo Lee, João A.C. Lima, Joseph Loscalzo, Naveen L. Pereira, Mark W. Russell, Svati H. Shah, Farah Sheikh, Thomas J. Wang and Calum A. MacRae On behalf of the American Heart Association Council on Genomic and Precision Medicine; Council on Cardiovascular Disease in the Young; Council on Cardiovascular and Stroke Nursing; Council on Cardiovascular Radiology and Intervention; Council on Peripheral Vascular Disease; Council on Quality of Care and Outcomes Research; and Stroke Council

Circ Genom Precis Med. 2018;11:e000046, originally published May 29, 2018
https://doi.org/10.1161/HCG.0000000000000046

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Genetic Variation and the ElectrocardiographFrom Genome-Wide Association Studies to the Patient
Paula L. Hedley, Christian M. Hagen and Michael Christiansen

Circ Genom Precis Med. 2018;11:e002164, originally published May 10, 2018
https://doi.org/10.1161/CIRCGEN.118.002164

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Outcomes of Contemporary Family Screening in Hypertrophic Cardiomyopathy
Hannah G. van Velzen, Arend F.L. Schinkel, Sara J. Baart, Rogier A. Oldenburg, Ingrid M.E. Frohn-Mulder, Marjon A. van Slegtenhorst and Michelle Michels

Circ Genom Precis Med. 2018;11:e001896, originally published April 16, 2018
https://doi.org/10.1161/CIRCGEN.117.001896

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Is Careful Assessment of Rare Variants in the RYR2 Gene Piercing the Guidelines’ Strong Armor?
Peter J. Schwartz and Maria-Christina Kotta

Circ Genom Precis Med. 2018;11:e002072, originally published February 16, 2018
https://doi.org/10.1161/CIRCGEN.118.002072

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Induced Pluripotent Stem Cells for Cardiovascular Disease Modeling and Precision Medicine: A Scientific Statement From the American Heart Association
Kiran Musunuru, Farah Sheikh, Rajat M. Gupta, Steven R. Houser, Kevin O. Maher, David J. Milan, Andre Terzic and Joseph C. Wu On behalf of the American Heart Association Council on Functional Genomics and Translational Biology; Council on Cardiovascular Disease in the Young; and Council on Cardiovascular and Stroke Nursing

Circ Genom Precis Med. 2018;11:e000043, originally published January 12, 2018
https://doi.org/10.1161/HCG.0000000000000043

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Unraveling the Puzzle of the Role of Heritability in the Variability of the QT Interval Using Exome Array Analysis
J. Martijn Bos and Naveen L. Pereira

Circ Genom Precis Med. 2018;11:e002007, originally published January 11, 2018
https://doi.org/10.1161/CIRCGEN.117.002007

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Surviving Sudden DeathWhere Does Next-Generation Sequencing Fit in the Assessment of Sudden Death Victims and Their Families
Robert M. Hamilton, Kristopher S. Cunningham and Elijah R. Behr

Circulation: Genomic and Precision Medicine. 2017;10:e002015, originally published December 15, 2017
https://doi.org/10.1161/CIRCGENETICS.117.002015

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Personalized AnticoagulationCLINICAL PERSPECTIVEOptimizing Warfarin Management Using Genetics and Simulated Clinical Trials
Kourosh Ravvaz, John A. Weissert, Christian T. Ruff, Chih-Lin Chi and Peter J. Tonellato

Circulation: Genomic and Precision Medicine. 2017;10:e001804, originally published December 13, 2017
https://doi.org/10.1161/CIRCGENETICS.117.001804

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