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Volume 2, Issue 1; February, 2009
Editorials
Original Articles
Advances in Genetics
Methods in Genetics and Clinical Interpretation
Controversies in Cardiovascular Genetics
Cardiovascular Genetics: A News Round-Up
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Editorials
Contemporary Approaches to Gene Discovery: Progress Toward Personalized Medicine?
Ingrid B. Borecki
Circ Cardiovasc Genet. 2009;2:1-2, doi:10.1161/CIRCGENETICS.109.850370
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A Gene-Centric Approach to Elucidating Cardiovascular Risk
Ruth McPherson
Circ Cardiovasc Genet. 2009;2:3-6, doi:10.1161/CIRCGENETICS.109.848986
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Original Articles
Prediction of Cardiovascular Disease Outcomes and Established Cardiovascular Risk Factors by Genome-Wide Association Markers
John P.A. Ioannidis
Circ Cardiovasc Genet. 2009;2:7-15; published online before print January 23 2009, doi:10.1161/CIRCGENETICS.108.833392
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Clinical Perspective
Genetic Variants Associated With Myocardial Infarction Risk Factors in Over 8000 Individuals From Five Ethnic Groups: The INTERHEART Genetics Study
Sonia S. Anand, Changchun Xie, Guillaume Paré, Alexandre Montpetit, Sumathy Rangarajan, Matthew J. McQueen, Heather J. Cordell, Bernard Keavney, Salim Yusuf, Thomas J. Hudson, James C. Engert on Behalf of the INTERHEART Investigators
Circ Cardiovasc Genet. 2009;2:16-25; published online before print January 23 2009, doi:10.1161/CIRCGENETICS.108.813709
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Clinical Perspective
Polymorphism in the
CETP
Gene Region, HDL Cholesterol, and Risk of Future Myocardial Infarction: Genomewide Analysis Among 18 245 Initially Healthy Women From the Womens Genome Health Study
Paul M. Ridker, Guillaume Paré, Alex N. Parker, Robert Y.L. Zee, Joseph P. Miletich, and Daniel I. Chasman
Circ Cardiovasc Genet. 2009;2:26-33; published online before print January 23 2009, doi:10.1161/CIRCGENETICS.108.817304
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Clinical Perspective
HFE
C282Y Homozygosity Is Associated With Lower Total and Low-Density Lipoprotein Cholesterol: The Hemochromatosis and Iron Overload Screening Study
Paul C. Adams, James S. Pankow, James C. Barton, Ron T. Acton, Cathie Leiendecker-Foster, Gordon D. McLaren, Mark Speechley, and John H. Eckfeldt
Circ Cardiovasc Genet. 2009;2:34-37; published online before print January 23 2009, doi:10.1161/CIRCGENETICS.108.813089
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Clinical Perspective
Association of Regions on Chromosomes 6 and 7 With Blood Pressure in Nigerian Families
Bamidele O. Tayo, Amy Luke, Xiaofeng Zhu, Adebowale Adeyemo, and Richard S. Cooper
Circ Cardiovasc Genet. 2009;2:38-45; published online before print January 23 2009, doi:10.1161/CIRCGENETICS.108.817064
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Clinical Perspective
Autonomic Function in Hypertension: Role of Genetic Variation at the Catecholamine Storage Vesicle Protein Chromogranin B
Kuixing Zhang, Fangwen Rao, Brinda K. Rana, Jiaur R. Gayen, Federico Calegari, Angus King, Patrizia Rosa, Wieland B. Huttner, Mats Stridsberg, Manjula Mahata, Sucheta Vaingankar, Vafa Mahboubi, Rany M. Salem, Juan L. Rodriguez-Flores, Maple M. Fung, Douglas W. Smith, Nicholas J. Schork, Michael G. Ziegler, Laurent Taupenot, Sushil K. Mahata, and Daniel T. O'Connor
Circ Cardiovasc Genet. 2009;2:46-56; published online before print January 23 2009, doi:10.1161/CIRCGENETICS.108.785659
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Clinical Perspective
An Evaluation of Candidate Genes of Inflammation and Thrombosis in Relation to the Risk of Venous Thromboembolism: The Womens Genome Health Study
Robert Y.L. Zee, Robert J. Glynn, Suzanne Cheng, Lori Steiner, Lynda Rose, and Paul M Ridker
Circ Cardiovasc Genet. 2009;2:57-62; published online before print January 23 2009, doi:10.1161/CIRCGENETICS.108.801969
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Clinical Perspective
Advances in Genetics
Genome-Wide Association Studies for Atherosclerotic Vascular Disease and Its Risk Factors
Keyue Ding and Iftikhar J. Kullo
Circ Cardiovasc Genet. 2009;2:63-72, doi:10.1161/CIRCGENETICS.108.816751
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Methods in Genetics and Clinical Interpretation
Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium: Design of Prospective Meta-Analyses of Genome-Wide Association Studies From 5 Cohorts
Bruce M. Psaty, Christopher J. O'Donnell, Vilmundur Gudnason, Kathryn L. Lunetta, Aaron R. Folsom, Jerome I. Rotter, André G. Uitterlinden, Tamara B. Harris, Jacqueline C.M. Witteman, Eric Boerwinkle on Behalf of the CHARGE Consortium
Circ Cardiovasc Genet. 2009;2:73-80, doi:10.1161/CIRCGENETICS.108.829747
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Controversies in Cardiovascular Genetics
How should hypertrophic cardiomyopathy be classified?: Whats in a Name? Dilemmas in Nomenclature Characterizing Hypertrophic Cardiomyopathy and Left Ventricular Hypertrophy
Barry J. Maron, Christine E. Seidman, Michael J. Ackerman, Jeffrey A. Towbin, Martin S. Maron, Steve R. Ommen, Rick A. Nishimura, and Bernard J. Gersh
Circ Cardiovasc Genet. 2009;2:81-86, doi:10.1161/CIRCGENETICS.108.788703
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Response
How should hypertrophic cardiomyopathy be classified?: Molecular Diagnosis for Hypertrophic Cardiomyopathy: Not Ready for Prime Time
Perry Elliott and William J. McKenna
Circ Cardiovasc Genet. 2009;2:87-89, doi:10.1161/CIRCGENETICS.108.835645
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Cardiovascular Genetics: A News Round-Up
Summary of Recent Articles of Interest
Wolfgang Lieb and Ramachandran S. Vasan
Circ Cardiovasc Genet. 2009;2:90-94, doi:10.1161/CIRCGENETICS.108.842336
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