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Volume 2, Issue 3; June, 2009
Editorial
Original Articles
Advances in Molecular Genetics, Genomics, Proteomics, Metabolomics, and Systems Biology
Cardiovascular Genetics: A News Round-Up
Correspondence
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Editorial
The Report Card on Growth Differentiation Factor 15: Consistent Marks But Not Yet Ready for Promotion
Anand Rohatgi and James A. de Lemos
Circ Cardiovasc Genet. 2009;2:209-211, doi:10.1161/CIRCGENETICS.109.874511
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Original Articles
Evidence for Coregulation of Myocardial Gene Expression by MEF2 and NFAT in Human Heart Failure
Mary E. Putt, Sridhar Hannenhalli, Yun Lu, Philip Haines, Hareesh R. Chandrupatla, Edward E. Morrisey, Kenneth B. Margulies, and Thomas P. Cappola
Circ Cardiovasc Genet. 2009;2:212-219; published online before print March 31 2009, doi:10.1161/CIRCGENETICS.108.816686
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Data Supplement
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Clinical Perspective
Quantitative Trait Locus Analysis of Neointimal Formation in an Intercross Between C57BL/6 and C3H/HeJ Apolipoprotein E–Deficient Mice
Zuobiao Yuan, Hong Pei, Drew J. Roberts, Zhimin Zhang, Jessica S. Rowlan, Alan H. Matsumoto, and Weibin Shi
Circ Cardiovasc Genet. 2009;2:220-228; published online before print April 21 2009, doi:10.1161/CIRCGENETICS.108.792499
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Clinical Perspective
The Relation of Genetic and Environmental Factors to Systemic Inflammatory Biomarker Concentrations
Renate B. Schnabel, Kathryn L. Lunetta, Martin G. Larson, Josée Dupuis, Izabella Lipinska, Jian Rong, Ming-Huei Chen, Zhenming Zhao, Jennifer F. Yamamoto, James B. Meigs, Viviane Nicaud, Claire Perret, Tanja Zeller, Stefan Blankenberg, Laurence Tiret, John F. Keaney, Jr, Ramachandran S. Vasan, and Emelia J. Benjamin
Circ Cardiovasc Genet. 2009;2:229-237; published online before print March 31 2009, doi:10.1161/CIRCGENETICS.108.804245
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Clinical Perspective
Association of Blood Lipids With Common DNA Sequence Variants at 19 Genetic Loci in the Multiethnic United States National Health and Nutrition Examination Survey III
Mary E. Keebler, Christopher L. Sanders, Aarti Surti, Candace Guiducci, Noel P. Burtt, and Sekar Kathiresan
Circ Cardiovasc Genet. 2009;2:238-243; published online before print April 14 2009, doi:10.1161/CIRCGENETICS.108.829473
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Clinical Perspective
Common Coding Variants of the
HNF1A
Gene Are Associated With Multiple Cardiovascular Risk Phenotypes in Community-Based Samples of Younger and Older European-American Adults: The Coronary Artery Risk Development in Young Adults Study and The Cardiovascular Health Study
Alexander P. Reiner, Myron D. Gross, Christopher S. Carlson, Suzette J. Bielinski, Leslie A. Lange, Myriam Fornage, Nancy S. Jenny, Jeremy Walston, Russell P. Tracy, O. Dale Williams, David R. Jacobs, Jr, and Deborah A. Nickerson
Circ Cardiovasc Genet. 2009;2:244-254; published online before print April 6 2009, doi:10.1161/CIRCGENETICS.108.839506
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Clinical Perspective
The
FTO
Gene Is Associated With an Atherogenic Lipid Profile and Myocardial Infarction in Patients With Type 2 Diabetes: A Genetics of Diabetes Audit and Research Study in Tayside Scotland (Go-DARTS) Study
Alex S.F. Doney, Jennifer Dannfald, Charlotte H. Kimber, Louise A. Donnelly, Ewan Pearson, Andrew D. Morris, and Colin N.A. Palmer
Circ Cardiovasc Genet. 2009;2:255-259; published online before print March 30 2009, doi:10.1161/CIRCGENETICS.108.822320
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Clinical Perspective
A Common Variant of the
FTO
Gene Is Associated With Not Only Increased Adiposity but Also Elevated Blood Pressure in French Canadians
Zdenka Pausova, Catriona Syme, Michal Abrahamowicz, Yongling Xiao, Gabriel T. Leonard, Michel Perron, Louis Richer, Suzanne Veillette, George Davey Smith, Ondrej Seda, Johanne Tremblay, Pavel Hamet, Daniel Gaudet, and Tomas Paus
Circ Cardiovasc Genet. 2009;2:260-269; published online before print March 31 2009, doi:10.1161/CIRCGENETICS.109.857359
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Clinical Perspective
A Mutation in the β3 Subunit of the Cardiac Sodium Channel Associated With Brugada ECG Phenotype
Dan Hu, Hector Barajas-Martinez, Elena Burashnikov, Michael Springer, Yuesheng Wu, Andras Varro, Ryan Pfeiffer, Tamara T. Koopmann, Jonathan M. Cordeiro, Alejandra Guerchicoff, Guido D. Pollevick, and Charles Antzelevitch
Circ Cardiovasc Genet. 2009;2:270-278; published online before print April 21 2009, doi:10.1161/CIRCGENETICS.108.829192
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Clinical Perspective
Impact of Adding a Single Allele in the 9p21 Locus to Traditional Risk Factors on Reclassification of Coronary Heart Disease Risk and Implications for Lipid-Modifying Therapy in the Atherosclerosis Risk in Communities Study
Ariel Brautbar, Christie M. Ballantyne, Kim Lawson, Vijay Nambi, Lloyd Chambless, Aaron R. Folsom, James T. Willerson, and Eric Boerwinkle
Circ Cardiovasc Genet. 2009;2:279-285; published online before print April 21 2009, doi:10.1161/CIRCGENETICS.108.817338
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Clinical Perspective
Growth-Differentiation Factor-15 for Risk Stratification in Patients With Stable and Unstable Coronary Heart Disease: Results From the AtheroGene Study
Tibor Kempf, Jan-Malte Sinning, Anja Quint, Christoph Bickel, Christoph Sinning, Philipp S. Wild, Renate Schnabel, Edith Lubos, Hans J. Rupprecht, Thomas Münzel, Helmut Drexler, Stefan Blankenberg, and Kai C. Wollert
Circ Cardiovasc Genet. 2009;2:286-292; published online before print March 31 2009, doi:10.1161/CIRCGENETICS.108.824870
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Clinical Perspective
Advances in Molecular Genetics, Genomics, Proteomics, Metabolomics, and Systems Biology
Ethical Challenges Encountered in Genomic Research
Patricia A. Roche
Circ Cardiovasc Genet. 2009;2:293-297, doi:10.1161/CIRCGENETICS.108.846758
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Cardiovascular Genetics: A News Round-Up
Summary of Recent Articles of Interest
Wolfgang Lieb and Ramachandran S. Vasan
Circ Cardiovasc Genet. 2009;2:298-302, doi:10.1161/CIRCGENETICS.109.874875
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Correspondence
Letter by Sullivan Regarding Article, "HFE C282Y Homozygosity Is Associated With Lower Total and Low-Density Lipoprotein Cholesterol: the Hemochromatosis and Iron Overload Screening Study"
Jerome L. Sullivan
Circ Cardiovasc Genet. 2009;2:e1, doi:10.1161/CIRCGENETICS.109.863860
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