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Volume 2, Issue 4; August, 2009
Editorial
Original Articles
Advances in Molecular Genetics, Genomics, Proteomics, Metabolomics, and Systems Biology
Cardiovascular Genetics: A News Round-Up
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Editorial
Pathways of the Heart
Rahul C. Deo and Frederick P. Roth
Circ Cardiovasc Genet. 2009;2:303-305, doi:10.1161/CIRCGENETICS.109.892588
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Original Articles
Clinical and Functional Characterization of
TNNT2
Mutations Identified in Patients With Dilated Cardiomyopathy
Ray E. Hershberger, Jose Renato Pinto, Sharie B. Parks, Jessica D. Kushner, Duanxiang Li, Susan Ludwigsen, Jason Cowan, Ana Morales, Michelle S. Parvatiyar, and James D. Potter
Circ Cardiovasc Genet. 2009;2:306-313; published online before print May 15 2009, doi:10.1161/CIRCGENETICS.108.846733
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Clinical Perspective
Echocardiographic Strain Imaging to Assess Early and Late Consequences of Sarcomere Mutations in Hypertrophic Cardiomyopathy
Carolyn Y. Ho, Christian Carlsen, Jens Jakob Thune, Ole Havndrup, Henning Bundgaard, Faranak Farrohi, Jose Rivero, Allison L. Cirino, Paal Skytt Andersen, Michael Christiansen, Barry J. Maron, E. John Orav, and Lars Køber
Circ Cardiovasc Genet. 2009;2:314-321; published online before print June 19 2009, doi:10.1161/CIRCGENETICS.109.862128
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Clinical Perspective
A Genome-Wide Association Scan of RR and QT Interval Duration in 3 European Genetically Isolated Populations: The EUROSPAN Project
Fabio Marroni, Arne Pfeufer, Yurii S. Aulchenko, Christopher S. Franklin, Aaron Isaacs, Irene Pichler, Sarah H. Wild, Ben A. Oostra, Alan F. Wright, Harry Campbell, Jacqueline C. Witteman, Stefan Kääb, Andrew A. Hicks, Ulf Gyllensten, Igor Rudan, Thomas Meitinger, Cristian Pattaro, Cornelia M. van Duijn, James F. Wilson, Peter P. Pramstaller on behalf of the EUROSPAN Consortium
Circ Cardiovasc Genet. 2009;2:322-328; published online before print May 15 2009, doi:10.1161/CIRCGENETICS.108.833806
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Clinical Perspective
Genome-Wide Association Scan Identifies Variants near
Matrix Metalloproteinase
(
MMP
) Genes on Chromosome 11q21–22 Strongly Associated With Serum MMP-1 Levels
Yu-Ching Cheng, Wen-Hong L. Kao, Braxton D. Mitchell, Jeffrey R. O'Connell, Haiqing Shen, Patrick F. McArdle, Quince Gibson, Kathleen A. Ryan, Alan R. Shuldiner, and Toni I. Pollin
Circ Cardiovasc Genet. 2009;2:329-337; published online before print May 14 2009, doi:10.1161/CIRCGENETICS.108.834986
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Clinical Perspective
9p21 is a Shared Susceptibility Locus Strongly for Coronary Artery Disease and Weakly for Ischemic Stroke in Chinese Han Population
Hu Ding, Yujun Xu, Xiaojing Wang, Qi Wang, Lan Zhang, Yuanchao Tu, Jiangtao Yan, Wei Wang, Rutai Hui, Cong-Yi Wang, and Dao Wen Wang
Circ Cardiovasc Genet. 2009;2:338-346; published online before print May 28 2009, doi:10.1161/CIRCGENETICS.108.810226
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Clinical Perspective
The 9p21 Myocardial Infarction Risk Allele Increases Risk of Peripheral Artery Disease in Older People
Christie Cluett, Mary McGrae McDermott, Jack Guralnik, Luigi Ferrucci, Stefania Bandinelli, Iva Miljkovic, Joseph M. Zmuda, Rongling Li, Greg Tranah, Tamara Harris, Neil Rice, William Henley, Timothy M. Frayling, Anna Murray, and David Melzer
Circ Cardiovasc Genet. 2009;2:347-353; published online before print June 23 2009, doi:10.1161/CIRCGENETICS.108.825935
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Clinical Perspective
Longitudinal Association of PCSK9 Sequence Variations With Low-Density Lipoprotein Cholesterol Levels: The Coronary Artery Risk Development in Young Adults Study
Chiang-Ching Huang, Myriam Fornage, Donald M. Lloyd-Jones, Gina S. Wei, Eric Boerwinkle, and Kiang Liu
Circ Cardiovasc Genet. 2009;2:354-361; published online before print June 10 2009, doi:10.1161/CIRCGENETICS.108.828467
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CACNA1C
Gene Polymorphisms, Cardiovascular Disease Outcomes, and Treatment Response
Amber L. Beitelshees, Hrishikesh Navare, Danxin Wang, Yan Gong, Jennifer Wessel, James I. Moss, Taimour Y. Langaee, Rhonda M. Cooper-DeHoff, Wolfgang Sadee, Carl J. Pepine, Nicolas J. Schork, and Julie A. Johnson
Circ Cardiovasc Genet. 2009;2:362-370; published online before print June 3 2009, doi:10.1161/CIRCGENETICS.109.857839
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Cardiac Resynchronization Therapy Corrects Dyssynchrony-Induced Regional Gene Expression Changes on a Genomic Level
Andreas S. Barth, Takeshi Aiba, Victoria Halperin, Deborah DiSilvestre, Khalid Chakir, Carlo Colantuoni, Richard S. Tunin, Victoria Lea Dimaano, Wayne Yu, Theodore P. Abraham, David A. Kass, and Gordon F. Tomaselli
Circ Cardiovasc Genet. 2009;2:371-378; published online before print May 15 2009, doi:10.1161/CIRCGENETICS.108.832345
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Clinical Perspective
Proteomics, Metabolomics, and Immunomics on Microparticles Derived From Human Atherosclerotic Plaques
Manuel Mayr, David Grainger, Ursula Mayr, Aurelie S. Leroyer, Guy Leseche, Anissa Sidibe, Olivier Herbin, Xiaoke Yin, Aldrin Gomes, Bassetti Madhu, John R. Griffiths, Qingbo Xu, Alain Tedgui, and Chantal M. Boulanger
Circ Cardiovasc Genet. 2009;2:379-388; published online before print May 14 2009, doi:10.1161/CIRCGENETICS.108.842849
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Clinical Perspective
Prolactin Levels and the Risk of Future Coronary Artery Disease in Apparently Healthy Men and Women
Anne Q. Reuwer, Marcel ThB Twickler, Barbara A. Hutten, Frederique W. Molema, Nicholas J. Wareham, Geesje M. Dallinga-Thie, Roman L. Bogorad, Vincent Goffin, Mijke Smink-Bol, John J.P. Kastelein, S. Matthijs Boekholdt, and Kay-Tee Khaw
Circ Cardiovasc Genet. 2009;2:389-395; published online before print June 23 2009, doi:10.1161/CIRCGENETICS.109.853572
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Clinical Perspective
Social- and Behavioral-Specific Genetic Effects on Blood Pressure Traits: The Strong Heart Family Study
Nora Franceschini, Kathryn M. Rose, Kristi L. Storti, Sue Rutherford, V. Saroja Voruganti, Sandy Laston, Harald H.H. Göring, Thomas D. Dyer, Jason G. Umans, Elisa T. Lee, Lyle G. Best, Richard R. Fabsitz, Shelley A. Cole, Jean W. MacCluer, and Kari E. North
Circ Cardiovasc Genet. 2009;2:396-401; published online before print June 16 2009, doi:10.1161/CIRCGENETICS.109.853630
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Advances in Molecular Genetics, Genomics, Proteomics, Metabolomics, and Systems Biology
MicroRNAs in Cardiovascular Biology and Heart Disease
Daniele Catalucci, Paolo Gallo, and Gianluigi Condorelli
Circ Cardiovasc Genet. 2009;2:402-408, doi:10.1161/CIRCGENETICS.109.857425
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Cardiovascular Genetics: A News Round-Up
Summary of Interesting Articles
Wolfgang Lieb and Ramachandran S. Vasan
Circ Cardiovasc Genet. 2009;2:409-414, doi:10.1161/CIRCGENETICS.109.887067
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